Continuous-wave plasma-generated electric field in 3D collagen gel during cold atmospheric plasma treatment
Статья в журнале
Cold atmospheric plasma (CAP) devices based on plasma jet with helium flow are actively used nowadays in the studies of cancer treatment. In addition to well-known factors produced by CAP devices (reactive chemical species, UV radiation, heat) that can reduce the viability of cancer cells, the effect of alternating continuous-wave non-thermal electromagnetic fields generated by plasma source inside the tissue remains unclear. In this article we measured the values and frequency composition of the continuous-wave electric field induced inside the model of the living tissue – a 3D artificial tissue composed of bovine type I collagen gel – during its irradiation by a helium plasma jet using the set of the probes immersed into the gel. It was found that the electric field in artificial tissue has strong DC with the main discharge frequency components, and at least up to four harmonics of the discharge frequency. E-field absolute values in artificial tissue during plasma treatment was within 300 – 30 000 V/m, which is significantly lower than estimated cell membrane field of about ~107 V/m. The absolute value of e-field DC component non-monotonically depends on discharge frequency with optimal frequency range of 14-16 kHz dependent of the thickness of the artificial tissue.
Журнал:
- Plasma Processes and Polymers
- Wiley - VCH Verlag GmbH & CO. KGaA (Berlin)
- Индексируется в Scopus, Web of Science
Библиографическая запись: Continuous‐wave plasma‐generated electric field in 3D collagen gel during cold atmospheric plasma treatment / D. B. Zolotukhin [et al.] // Plasma Processes and Polymers. – 2019. – Vol. 16. – Iss. 12. – P. 1900129. – DOI: 10.1002/ppap.201900129
Индексируется в:
- Scopus ( https://www.scopus.com/record/display.uri?eid=2-s2.0-85070940005&origin=resultslist )
- Web of science ( https://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=20&SID=D1KQ3wlIGnccCD83ima&page=1&doc=1 )
- РИНЦ ( https://www.elibrary.ru/item.asp?id=41643800 )